Chen et.al reported that Linc-RoR can promote proliferation, migration, and invasion via the Hippo/YAP pathway in pancreatic cancer cells (17).In this study, we investigated the expression pattern and clinical significance of LINC00518 in LUAD tissues by searching the microarray data set published in the TCGA database, and found that the expression of LINC00518 in LUAD tissues and cell lines were significantly up-regulated and the increased LINC00518 expression may be related to a poor survival rate. This evidence concerns the gene LINC00518 and pancreatic neoplasm.