TNFRSF12A expression in GBM patients showed a positive correlation with two classical immune checkpoints CD274 (cor = 0.452, p = 6.44e-09) and PDCD1LG2 (cor = 0.234, p = 3.73e-03), while LAG3 (cor = −0.206, p = 1.07e-02) exhibited a negative correlation (Figure 11D). Here, CD274 is linked to glioblastoma.