In 2020 Sun MY (64) demonstrated that RPS3 (Ribosomal Protein S3) expression levels were significantly elevated in cisplatin-resistant gastric cancer cell line SGC7901 and the exosomal delivery of RPS3 might induce chemoresistance phenotypes from cisplatin-resistant gastric cancer cells to sensitive cancer cells by regulating the PI3K-Akt-cofilin-1 signaling pathway. The gene discussed is AKT1; the disease is gastric cancer.