We further analyze the CHI3L2 mRNA expression levels in new molecular classification of diffusely infiltrating glioma, including IDH mutant without 1p/19q codeleted gliomas, IDH mutant with 1p/19q codeleted gliomas, and IDH wild-type gliomas, in TCGA and CGGA database (Figure S4A and Figure S4B). The gene discussed is CHI3L2; the disease is central nervous system cancer.