A significant increase in overall concentrations of EVs (Bodipy+; Figure 8a) as well EVs from monocytes (CD14+/CD41–; Figure 8b), platelets (CD14–/CD41+; Figure 8c) and double positive (CD14+/CD41+ EVs; Figure 8d) was quantified in the plasma of CAD patients who needed stenting. The gene discussed is ITGA2B; the disease is coronary artery disorder.