APOE and metabolic syndrome: The levels of the oxidative stress biomarkers, including MPO, are higher in women with RPL exhibiting metabolic syndrome, and the oxidative stress, subclinical inflammatory state, and metabolic syndrome contribute to pregnancy outcome prediction in women with RPL [33], thus suggesting that in RSA, IL-1B, PTGS2, APOE, and MPO might also be targeted by Wenjing decoction.