Another review in 2001 by Kiss et al. on the expression of Gal-8 in benign and malignant epithelial, mesenchymal and even neurological tumors in different parts of the body showed decrease in expression of Gal-8 in malignant tumors compared with normal and benign tumors in colon (P=0.001), pancreas (P=0.007), liver (P=0.0008), skin (P=0.002) and larynx (P=0.02), respectively. Here, LGALS8 is linked to benign neoplasm.