Figure 6C represents an area at the tumor front where macrophages infiltrate the tumor islet, while T lymphocytes boarder the tumor edges. Figure 6D focuses on a fiber-rich area, in which few immune cells are found, while dense tenascin C fibrils line the border of the tumor islet, and by contrast, fibronectin fibrils occupy other areas of the stroma more distant from tumor islets. Finally, Figure 6E depicts an immune cell rich area. Here, TNC is linked to neoplasm.