In the present study, we used ESTIMATE and CIBERSORT algorithm to quantify the tumor-infiltrating immune cell (TIC) proportion and the ratio of immune and stromal components of BRCA samples from the gene expression omnibus (GEO) database and identified a novel predictive biomarker, ATPase Secretory Pathway Ca2+ Transporting 2 (ATP2C2). Here, ATP2C2 is linked to neoplasm.