CD8A and viral infectious disease: For a systematic estimation of the potential number of viral-human zwitter epitope candidates that could (i) be presented by HLA-I complexes, (ii) be involved in an autoimmune CD8+ T cell response in T1D patients, and (iii) be at least in part triggered by viral infection, we started from the foundations: we computed the number of 9mer peptides that might originate from human proteome, as well as those that might originate from T1D-associated viruses (Table S3).