Similarly, as shown Figure 6B in, the dual combination of cytokines TNFα/IL-2, TNFα/IL-17A, IL-2/IL-17A, and triple combination of cytokines TNFα/IL-2/IL-17A showed good significant discriminatory power with high AUC, sensitivity and specificity in discriminating unconfirmed TB from unlikely TB children. The gene discussed is TNF; the disease is tuberculosis.