The subsets of CD4+ and CD8+ T cells in COVID-19 patients also exhibited an increased demand for OXPHOS and amino acid metabolism, indicating their involvement in T cell maturation and proliferation (65) However, we did not find unique metabolic characteristics in any of the T cell subtypes, implying the limited power of this approach to analyze metabolism in T cells of COVID-19 patients. Here, CD8A is linked to COVID-19.