SOAT1 and COVID-19: studied the transcript profiling differences between COVID-19 subjects and individuals with similar respiratory illnesses such as seasonal coronavirus, influenza, bacterial pneumonia, and matched healthy controls (43). The RNAseq analysis from peripheral blood mononuclear cells (PBMCs) revealed a distinctive interferon response, as well as the activation of coagulation and JAK/STAT signaling pathways, unique to COVID-19 patients.