Furthermore, we examined the co-localization between AhR and RhoA in the lung tissues of an asthma mouse model (Figure 5E) and found a clear overlapping between AhR and RhoA-GTP in the airways of either BaP or Der f 1 alone or co-exposure-treated mice, supporting that there might be an interaction between AhR and RhoA. The gene discussed is RHOA; the disease is asthma.