Respiratory allergy and allergic asthma share 1 highly related protein, specifically IL-4R, which has been identified as an effector of the acute phase of allergy (60) and receptor of IL-4 and IL-13, molecules that have been proven to regulate IgE synthesis (45) and have been detected to be over-expressed in acute asthmatics. The gene discussed is IL4R; the disease is allergic asthma.