Furthermore, exogenous LXA4 supplementation reduced renal dysfunction induced by sepsis, as evidenced by lower levels of serum BUN, SCr, urinary KIM-1, NGAL, and pathological scores than that in the CLP groups (Figure 3; all p < 0.001, CLP vs. LXA4 + CLP group). The gene discussed is HAVCR1; the disease is Sepsis.