Examples are studies that colocalized 31 RA-associated SNPs with H3K4me3 marks in CD4+ T cells (59), and colocalization of RNA-seq and ChIP-seq signals for the H3K4me1 and K3K27Ac enhancer marks in neutrophils and CD4+ T cells with JIA-associated variants in patients (60). The gene discussed is CD4; the disease is juvenile idiopathic arthritis.