Accordingly, 28 weeks of strength training can exert anti-inflammatory effects in older people, resulting into an increase in IL-10 levels occurring conjunctly with a slight decrease in the TNF- α/IL-10 ratio and maintenance of TNF-α levels in 33 older women with cognitive impairment, aged 82.7 ± 5.7 years (125). This evidence concerns the gene IL10 and Cognitive impairment.