The Post-transplant CD8 T cells suppressed by secreting mainly TGF-β and they expressed high levels of TGF-β latency-associated peptide (LAP), but they produced IL-10 to a much lesser extent; which is desirable because IL-10, by causing expansion of autoimmune B cells, is deleterious in lupus (136). This evidence concerns the gene TGFB1 and systemic lupus erythematosus.