Thus, natural killer (NK) cell activation markers, such as NKG2D, KLRC2, and KLRC4, ligands for NK receptor (CLEC2B), as well as markers of oxidative stress (CANP and POSTN) and innate immunity (DEFB103A) were shown to be increased in vitiligo skin (10). This evidence concerns the gene KLRK1 and vitiligo.