IL-1β, IL-6, IL-8, IL-10, IL-25, and the TSLP of NECs were significantly higher expressed in CRSwNP than in control subjects (P<0.05), and no significant difference of IL-33 was found in NECs between control subjects and CRSwNP (P>0.05) (Figures 2A-G). This evidence concerns the gene IL25 and chronic rhinosinusitis with nasal polyps.