Pyocin SD2-treated mice previously infected with PAO1 had no signs of illness and survived to end point (24 h post infection) and low counts of PAO1 were recovered from lungs (5 CFU/lung). Untreated infected mice were culled at 6 h due to severity of illness and high counts of PAO1 (105 CFU/lung). The gene discussed is SMOX; the disease is infection.