Blocking the interaction between the adhesion molecule CD44 and its ligand hyaluronan using an anti-CD44 antibody also exhibits a potential inflammation-controlling effect both in LPS-induced or diet-induced mouse models, but further research is still needed in NASH (McDonald et al., 2008; Kodama et al., 2015; McDonald and Kubes, 2015). The gene discussed is CD44; the disease is metabolic dysfunction-associated steatohepatitis.