PECAM1 and metabolic dysfunction-associated steatotic liver disease: Shown with a scanning electron microscopy or marker of capillarization indicators such as CD31 and CD34, the capillarization of LSECs was observed at the early stage of NAFLD in animal models induced by diet, including high fat diet (HFD), choline-deficient l-amino acid-defined (CDAA) diet, and high fat glucose-fructose diet (HFGFD) (Table 1) (Peng et al., 2014; Miyao et al., 2015; Bravo et al., 2019).