GSK3B and brain ischemia: A number of studies have indicated that inhibition of GSK-3β ameliorated cerebral ischemia injury (Chuang et al., 2011; Venna et al., 2015; Pang et al., 2016; Wang et al., 2017; Gao et al., 2020; Wen et al., 2020), consistent with our findings.