The topical application of a natural compound mixture (PSM) of herbs, containing emodin, genipin, chlorogenic acid, cimigenoside, and ginsenoside Rb1, alleviated IMQ-induced psoriasis-like dermatitis and reduced the proliferation rate of IL-22-stimulated keratinocytes (Nguyen et al., 2020b). Here, IL22 is linked to psoriasis.