DHTKD1 and infection: qRT-PCR analyses reveal that digoxin and digitoxin reduce genome levels at 20–22 h post-infection, altering RNA splicing of immediate-early protein (E1A) in the early stages of infection and partially blocking the RNA transition at late stages of adenovirus replication (strain HAdV-A31, -B35, -C5, and a species D conjunctivitis isolate) (Grosso et al., 2017).