Wang et al. (2010) showed that mouse peritoneal macrophages (PMs) treated with GSP could induce tumor killing activity, enhance phagocytic activity and the expression of CD68 and show the ability to produce cytokines and cytotoxic molecules. Kim et al. (2009) proved that GSP can induce the maturation of mouse bone marrow-derived DC, enhance the expression of CD86 on the surface of DCs, and significantly promote the proliferation of allogeneic CD4+T lymphocytes. Here, CD4 is linked to neoplasm.