CD276 and non-small cell lung carcinoma: Bamodu et al. (2019) proved that astragalus polysaccharides can significantly increase the polarization rate of M1/M2 macrophages in non-small cell lung cancer (NSCLC) cell lines, regulate the M1/M2 macrophage pool (M1 macrophages produce pro-inflammatory factors and enhance the expression of MHC-II and costimulatory molecules), enhancing the body’s immune response.