AKT1 and non-small cell lung carcinoma: It has previously been shown that Akt/mTOR acts as a classical negative modulator of autophagy induced by antitumor drugs (Green and Levine, 2014; Dou et al., 2016; Zhou L. et al., 2019), we thus evaluate whether the Akt/mTOR pathway was inhibited in GYZ-treated NSCLC cells.