AKT1 and stroke disorder: Zhuang et al. (2012) had undertaken a study to examine the promotive effect of salvianolic acid B (Sal B) on NSPC proliferation and neurogenesis. The result showed that Sal B was capable of promoting the proliferation of NSPC and neurogenesis via the PI3K/Akt signaling pathway. These findings suggested that it is possible that we could promote the recovery of stroke via endogenous stem cells.