These data suggest that CTLA4, SQSTM1, CDKN1B, GATA3, FASN, PARK7, BAX, RICTOR, NAPSA, PDK1, MACC1, PEA15, BCL2, GSK3A, GSK3B, TSC2, STAT3, AKT1, AKT2, AKT3, TSC1, AXL, PDCD1, MAPK1, MSH2, RPS6KB1, BID, MTOR, EIF4EBP1, BAP1, ETS1, KEAP1, XRCC5, ERBB3, TP63, CASP3, PXN, FOXO3 and NOTCH (P value < 0.05) were primarily correlated with genomic alterations of Kindlins in NSCLC. This evidence concerns the gene TSC2 and non-small cell lung carcinoma.