On the other hand, focusing on TP53, there was significantly higher AF in SCC than in IN and hyperplasia (35 [range, 10–85] vs. 11 [range, 4–73], p = 0.014, 35 [range, 10–85] vs. 9 [range, 5–55], p = 0.029, Kruskal–Wallis test), but not in background mucosa between groups (8 [range, 4–35], 18 [range, 8–30], and 6.5 [range, 5–10], respectively) (Figure 4B). The gene discussed is TP53; the disease is atrial fibrillation.