The immunohistochemical assay showed that 28 cases (75.7%) were positive for Fzd7 among the 37 cancer tissue samples and seven cases (18.9%) were positive for Fzd7 in the 37 paracancerous tissues, and the IHC scores were 6.2 ± 3.4 and 2.9 ± 3.1, respectively (p < 0.05). This evidence concerns the gene FZD7 and cancer.