So far, NK-92 cells have been tested in preclinical CAR-NK studies targeting AML (directed to CD33), lymphoma (CD19), myeloma (CS1), prostate cancer (EpCAM), breast cancer (Her2), neuroblastoma (GD2), glioblastoma (EGFR) and ovarian cancer (mesothelin). The gene discussed is ERBB2; the disease is breast carcinoma.