Furthermore, only patients with IBD had detectable ADAs in our cohort, begging the question whether the real-world dosing practices observed in our IBD cohort (median [IQR] of 7.7 [6.2,9.4] mg/kg every 6 [4,8] weeks) are adequate to prevent loss of treatment response to IFX. The gene discussed is AGPS; the disease is inflammatory bowel disease.