INS and type 2 diabetes mellitus: The top five strongest pathways by most significant p values for African Americans were linoleic acid metabolism with FAD2 (66.7%) and FAD1 (26.8%) genes, followed by insulin secretion and type 2 diabetes with insulin pathway (86.1% and 83.1%), respectively, in addition to vitamin A and carotenoid metabolism with CY26A1 (55%) and ALDH1A2 (38.6%), and maturity onset diabetes with insulin (82.2%).