PTH and multiple endocrine neoplasia type 1: Hypercalcemia is reportedly present in approximately 5–10 % of patients with acromegaly [1, 2] and is usually parathyroid hormone (PTH)-dependent as a result of a coexisting parathyroid hyperplasia or adenoma, which are common in individuals with multiple endocrine adenomatosis-1 (MEN-1) [3].