LRRC4 and amyotrophic lateral sclerosis: RNA sequencing results from spinal cord showed that LRRC4 deletion mainly affects neuroactive ligand-receptor interaction, dentate gyrus and hippocampus development, learning, memory and cognition, cell adhension, RNA processing and cellular response to interferon-garmma, astrocyte differentiation, and involving in amyotrophic lateral sclerosis, Huntington desease, viral myocarditis.