The reason for the predominance of staphylococcal infection remains unknown but likely relates to deficiency of Th17 lymphocytes, which release antimicrobial peptides and produce the IL-17 cytokine family implicated in the response to Staphylococcus aureus, Candida, and gram-negative bacteria [36–39]; their differentiation from naïve CD4 + T-lymphocytes depends on STAT3 [40]. Here, IL17A is linked to staphylococcal infection.