AKT1 and hypertrophic cardiomyopathy: KEGG pathway analysis highlighted that ECM–receptor interaction (P = 9.92E−9), focal adhesion (P = 2.14E−8), hypertrophic cardiomyopathy (P = 1.47E−3) and PI3K–Akt signaling pathway (P = 3.26E−3) were dysregulated (Fig. S2D).