In intestinal tissues of NEC patients, we observed that expression levels of GNA11, MYLK, MYOM1, NFIA, PRKCZ, and RGN were significantly downregulated (P < 0.02), with IL‐6 and IL‐8 significantly increased, compared with those from Surg‐CTL subjects (n = 10 for each group; Fig. S4). Here, IL6 is linked to necrotizing enterocolitis.