MMP1 and lung cancer: BACH1 also acts as a critical molecular regulator of breast cancer bone metastasis by activating the transcription of several functional metastatic genes, including MMP1 and CXCR4. 9Moreover, in human ovarian cancer, BACH1 promotes ovarian migration by interacting with HMGA2 and enhancing the transcription of EMT genes, including VIM, SNAI1, and SNAI2. 15In lung cancer, BACH1 expression stimulates glycolysis by activating HK2 transcription and triggers glycolysis‐dependent lung cancer metastasis.19