Ameliorated glomerular and tubular histology, decreased kidney expression of caspase‐1 and fraction of TUNEL‐positive cells (apoptosis) and kidney expression of NLRP3 and IL‐1β (inflammation) in a rat model of diabetes (Sahin et al., 2019); reduced levels of lipid peroxidation and oxidative injury products in renal tissue, improved histological appearance in a rat I/R model (Tok et al., 2012). The gene discussed is IL1B; the disease is diabetes mellitus.