Chr3q27.1‐q27.2 CN gain is one of these metastatic‐specific CNA candidates (Figures 5A‐5D) and is particularly interesting as this region harbors the IGF2BP2, SENP2, and ETV5 genes, overexpressed in samples carrying the gain, that were previously reported to have a pro‐oncogenic role in many types of cancers.34, 35, 36. Here, SENP2 is linked to cancer.