IL6 and lung cancer: Considering both CCL1 and CCL20, which screened as the most upregulated chemoattractants, are T cell attracting factors and mainly responsible for Treg cell migration to the TME in human breast and lung cancers,28, 29, 30 we identified other eight differential cytokines (IL1A, CXCL3, IL1B, IL23A, CXCL1, CCL2, CXCL8, and IL6) with higher local expressions, and verified by RT‐PCR analysis.