MAP2 and ischemia: In line with reports describing early ischemia-associated loss of MAP2 [39, 40, 65], the here presented immunofluorescence and Western blot analyses in mice and rats revealed that an ischemia-associated reduction of MAP2 occurs early (4h after MCAO) and uniformly throughout the infarct area (Figs. 1, 2, and 3, Suppl.