As ALS is characterized by decreased survival this is also a relevant parameter in the SOD1 G93A mouse model, but we did not find any significant difference (p = 0.12) between the SOD1 + P (median survival = 150 days) and SOD1 + E groups (only 1 mouse reached a neurological score of 4, and, therefore, no median survival can be calculated) (Fig. 1k). Here, SOD1 is linked to amyotrophic lateral sclerosis.