Thrombospondin 1 (THBS1) (3.26-fold; p-value ≤ 0.05) which was significantly overexpressed in OKF6/TERT1-Shammah cells has been documented to be elevated in OSCC specimens induced by TGFBI which further promotes tumor migration and invasion34. The gene discussed is THBS1; the disease is neoplasm.