CD8A and cancer: Tumor samples with higher average expression of “Inflammatory response” PRC2+-CGI genes showed higher cytotoxic activity of intratumoral CD8 + T cells in most cancer types (Supplementary Fig. 10d left panel and Fig. 4f), and this was the case for most of the 16 “Inflammatory response” genes individually (Supplementary Fig. 10d right panel and Supplementary Fig. 10e).