In addition, there was a statistically significant positive correlation between the interleukin-33 concentrations of the multiple trauma patients at time point 48 h with an r = 0.6478 (p value = 0.0292) and 72 h with an r = 0.6262 (p value = 0.0363) and the corresponding SIRS score on day 4. This evidence concerns the gene IL33 and systemic inflammatory response syndrome.