Furthermore, there was a statistically significant positive correlation between the interleukin-33 concentrations of the multiple trauma patients at time point 0 h with an r = 0.6691 (p value = 0.0390), 24 h with an r = 0.6188 (p value = 0.0355) and 48 h with an r = 0.6622 (p value = 0.0223) and the corresponding SIRS score on day 3. This evidence concerns the gene IL33 and systemic inflammatory response syndrome.