Previous studies have reported that some glycosyltransferases and glycosidases are associated with the phosphorylation of TGF-β receptors of TGF-β signaling, such as fucosyltransferase 8 (FUT 8) in lung cancer [80], sialylation in colon cancer [81] N-acetylglucosaminyl-transferase V (MGAT5, 37] and α2,3 sialytransferase 5,GM3 synthase (ST3GAL5) [26]. Here, MGAT5 is linked to malignant colon neoplasm.